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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Mesenchymal stem cells overexpressing hepatocyte nuclear factor-4 alpha alleviate liver injury by modulating anti-inflammatory functions in mice

Fig. 3

HNF-4α-MSCs inhibited Kupffer cell-associated inflammation. a Concentrations of the inflammatory factors TNF-α, IFN-γ and IL-6 were detected in mouse serum on the sixth week using a Bio-plex assay. b Expression of ALB was detected using IHC (× 320). c The Kupffer cell marker CD68 was detected in mouse livers using IHC (× 200). d Quantification of panel c. Three fields of view were selected for each group to count the CD68-positive cells. The mean of the three fields was used to represent the CD68+ cells for each group. (Five mice were used in each group. The data are represented as the mean ± S.D.) Scale bars, 100 μm

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