Fig. 3

GMSCs have no side effects in long-term toxicity test in rats. a GSMC influence on RBC related indexes, including hemoglobin concentration (HGB), hematocrit (HCT), erythrocyte mean corpuscular volume (MCV), mean corpuscular-hemoglobin concentration (MCHC), red blood cell distribution width (RDW), and (b) the percentage (%) of immune cells, including white blood cells (WBC), lymphocyte, monocytes (MONO), neutrophilic granulocyte (NEUT), basophilic granulocyte (BASO), eosinophilic granulocyte (EOS) by infusing GMSCs into rats in the first dose period (FP), withdrawal period (WP), and convalescence period (CP) respectively. GMSC effect on biochemical indexes (c) and H&E staining (d–e) of parts of important organ of rats. The data indicate the mean ± SD of three separated experiments. *p < 0.05, **p ≤ 0.01. N ≥ 6 rats/group