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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Elevated level of mitochondrial reactive oxygen species via fatty acid β-oxidation in cancer stem cells promotes cancer metastasis by inducing epithelial–mesenchymal transition

Fig. 3

RH-TS contributed to In Vivo cancer metastasis. a The pulmonary metastases of tumor spheres and RH-TS were much more than that of 4 T1 cells and RL-TS when orthotopically inoculated into Balb/c mouse. Five independent experiments. NS, not significant; ***, p < 0.001. b The liver metastases of tumor spheres and RH-TS were much more than that of HCT116 cells and RL-TS when inoculated subcutaneously into NOD/SCID mouse. Two independent experiments performed. NS, not significant; **, p < 0.01. c The liver metastases of tumor spheres and RH-TS were much more than that of SW480 cells and RL-TS when inoculated subcutaneously into NOD/SCID mouse. Two independent experiments performed. NS, not significant; **, p < 0.01. d The liver metastases of tumor spheres and RH-TS were much more than that of HT29 cells and RL-TS when inoculated subcutaneously into NOD/SCID mouse. Two independent experiments performed. NS, not significant; **, p < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512