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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Human embryonic stem cell-derived cardiomyocyte therapy in mouse permanent ischemia and ischemia-reperfusion models

Fig. 5

Inflammatory response in the PI and IR mice after cell transplantation. ELISA of TNF-α (a) and IL-6 (b) in mouse sera from the Sham group, PI groups treated with PBS or ESC-Rep-CMs, and IR groups treated with PBS or ESC-Rep-CMs, at day 1, day 3, and day 7 after cell transplantation. n = 3 per group. c Myeloperoxidase analysis (MPO) of left ventricles from different groups. n = 3 per group. Real-time PCR analysis of left ventricles for neutrophils surface receptor Cxcr1 (d) and Cxcr2 (e) expression. f ELISA of IL-10 in mouse sera from the Sham group, PI groups treated with PBS or ESC-Rep-CMs, and IR groups treated with PBS or ESC-Rep-CMs at day 1, day 3 and day 7 after cell transplantation. n = 3 per group. All data are presented as the mean ± SEM; one-way ANOVA; *p < 0.05, and ns, not significant

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