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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema

Fig. 3

Transplantation of LEPLCs downregulated the expression of inflammatory mediators in the PPE-induced pulmonary emphysema mouse model. Effects of LEPLCs treatment on the inflammatory response. Lung tissues were collected at week 6 post-PPE treatment for inflammatory-related genes, and mRNA expression levels of a pro-Il-1β, b, Il-6, c Inos, and d Mcp-1 were determined by quantitative real-time RT-PCR. Values were normalized to the Gapdh gene and expressed in relation to the PBS group. Data are represented as the mean ± SD; n ≥ 5 per group. *p < 0.05; **p < 0.01

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