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Table 4 Comparison of preDSCs and MSCs

From: Human predecidual stromal cells are mesenchymal stromal/stem cells and have a therapeutic effect in an immune-based mouse model of recurrent spontaneous abortion

Characteristics PreDSCs MSCs References
Antigen phenotype Table 1 Table 1 [5, 19, 36]
ISCT minimal criteria + + [19, 37]
Decidualization PRL (mRNA+, protein+) PRL (mRNA+, protein−) [5]
Mesenchymal differentiation + + This work, [37]
Cell contractility + + [19, 29]
Stem cell markers + + This work,[43]
Clonogenicity + + This work, [45]
Apoptosis resistance + + [27, 30]
Hematopoietic cell supportive activity + + [18, 46]
Survival in xenotransplants + + This work, [47, 48]
Perivascular location + + [19, 49]
In vivo and in vitro immunoregulatory activity + + This work [5, 7, 23]