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Table 4 Comparison of preDSCs and MSCs

From: Human predecidual stromal cells are mesenchymal stromal/stem cells and have a therapeutic effect in an immune-based mouse model of recurrent spontaneous abortion

Characteristics

PreDSCs

MSCs

References

Antigen phenotype

Table 1

Table 1

[5, 19, 36]

ISCT minimal criteria

+

+

[19, 37]

Decidualization

PRL (mRNA+, protein+)

PRL (mRNA+, protein−)

[5]

Mesenchymal differentiation

+

+

This work, [37]

Cell contractility

+

+

[19, 29]

Stem cell markers

+

+

This work,[43]

Clonogenicity

+

+

This work, [45]

Apoptosis resistance

+

+

[27, 30]

Hematopoietic cell supportive activity

+

+

[18, 46]

Survival in xenotransplants

+

+

This work, [47, 48]

Perivascular location

+

+

[19, 49]

In vivo and in vitro immunoregulatory activity

+

+

This work [5, 7, 23]