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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats

Fig. 2

Bone formation in irradiated bone defects and the expression of miR-34a in newly formed bone. a, b Micro-CT and H&E images of bone formation in bone defects of non-irradiated (0 Gy) and irradiated (15 Gy) rats 2, 4, and 8 weeks after surgery; scale bar of CT 2D images = 1.5 mm; scale bar of H&E images = 1 mm. d BV/TV in the cortical bone area. c BV/TV in the trabecular bone area. d Expression of miR-34a in the newly formed bone of non-irradiated (N-BD) or irradiated (IR-BD) rats. Data are shown as mean ± SD, n = 3; *p < 0.05. **p < 0.01, ***p < 0.001

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