Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Nortropane alkaloids as pharmacological chaperones in the rescue of equine adipose-derived mesenchymal stromal stem cells affected by metabolic syndrome through mitochondrial potentiation, endoplasmic reticulum stress mitigation and insulin resistance alleviation

Fig. 4

Anti-apoptotic effects of calystegines on EMSASCs cells. a Flow cytometry-based Annexin V/7-AAD representative plots. b Bar chart representation of total living and total apoptotic cell distribution expressed in percentage. c RT-qPCR analysis of relative expression of the main related apoptotic genes. Ctrl_HE healthy control cells, Ctrl_EMS EMS control cells, EMS_Cal 250 EMS cells treated with 250 μg/ml of calystegines, EMS_Cal 500 EMS cells treated with 500 μg/ml of calystegines. Values are mean ± SD (n = 3). Asterisk (*) refers to the comparison of EMS treated and untreated groups to untreated healthy cells, Hashtag (#) refers to the comparison of EMS treated groups to EMS untreated cells. */#p < 0.05, **/##p < 0.01, ***/###p < 0.001

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512