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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Nortropane alkaloids as pharmacological chaperones in the rescue of equine adipose-derived mesenchymal stromal stem cells affected by metabolic syndrome through mitochondrial potentiation, endoplasmic reticulum stress mitigation and insulin resistance alleviation

Fig. 7

RT-PCR analysis of insulin resistance markers after calystegine treatment on EMSASCs cells. a Gene expression levels of key factors involved in insulin signaling pathway. b Gene expression levels of lipid metabolism markers. Ctrl_HE healthy control cells. Ctrl_EMS EMS control cells, EMS_Cal 250 EMS cells treated with 250 μg/ml of calystegines, EMS_Cal 500 EMS cells treated with 500 μg/ml of calystegines. Results are expressed as mean of three independent experiments ± SD. Asterisk (*) refers to the comparison of EMS treated and untreated groups to untreated healthy cells. Hashtag (#) refers to the comparison of EMS treated groups to EMS untreated cells. */#p < 0.05, **/##p < 0.01, ***/###p < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512