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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: SDF-1/CXCR4 axis enhances the immunomodulation of human endometrial regenerative cells in alleviating experimental colitis

Fig. 5

CXCR4 high-expressing ERCs in increasing the percentage of Th2, Tregs, and M2 in DSS-induced colitis in mice. The spleen was dissected and made into a single-cell suspension. Cells were stained with fluorescently labeled CD4, IL-4, CD4, CD25, Foxp3, CD68, and CD206 and detected by flow cytometry. a Dot plots of Th2, Tregs, and M2 cells. b Percentage of Th2, Tregs, and M2 cells. #ERCs indicated ERCs pretreated with SDF-1. *ERCs indicated inhibition of the function of SDF-1 by AMD3100. The p value was determined by one-way ANOVA. ***p < 0.001, **p < 0.01, *p < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512