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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: SDF-1/CXCR4 axis enhances the immunomodulation of human endometrial regenerative cells in alleviating experimental colitis

Fig. 6

CXCR4 high-expressing ERCs modulated the balance of anti-inflammatory and pro-inflammatory cytokines in the injured colon, and CM-Dil-positive SDF-1-treated ERCs were found to be clustered. a Homogenized the colon samples and harvested the supernatants. The concentration of TNF-α, IL-4, IL-6, and IL-10 was measured by ELISA. b CM-Dil-positive SDF-1-treated ERCs were significantly detected in the injured colon tissue and spleen compared with CM-Dil-positive ERCs, but not in the kidney. #ERCs indicated ERCs pretreated with SDF-1. *ERCs indicated inhibition of the function of SDF-1 by AMD3100. The p value was determined by one-way ANOVA. ***p < 0.001, **p < 0.01, *p < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512