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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: BMP2 secretion from hepatocellular carcinoma cell HepG2 enhances angiogenesis and tumor growth in endothelial cells via activation of the MAPK/p38 signaling pathway

Fig. 1

High expression of BMP2 is found in HCC and positively correlates with angiogenesis in HCC. a Relative correlation between BMP2 and MVD in HCC. b Positive expression rate of BMP2 protein in HCC and adjacent normal tissues detected by immunohistochemistry (× 200). c Western blot analysis of BMP2 protein in THLE3, MHCC97, Hep3BLIP-I, HepG2, HCCLM3, and Huh7 cell lines. Data were expressed as mean ± standard deviation, and data between two groups were compared using Student’s t test. *p < 0.05. MVD, microvessel density; HCC, hepatocellular carcinoma; BMP2, bone morphogenetic proteins 2

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