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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system

Fig. 3

Transcriptome analysis of PEF-iPS and PC-iPS. (A, a) Heatmap analysis of PC-iPS cells, PEF-iPS cells, and different stages of pig embryos. (A, b) PCA analysis of PC-iPS cells, PEF-iPS cells, and different stages of pig embryos. (A, c) Expression analysis of endogenous and exogenous pluripotency-related transcription factors in PC-iPS and PEF-iPS cells cultured in LCDMV. (A, d) Expression analysis of other pluripotency-related genes in PC-iPS and PEF-iPS cells. (B, a) Heatmap analysis of PC-iPS vs PEF-iPS cells (P < 0.01). (B, b) Volcano plot of PC-iPS vs PEF-iPS cells. (B, c) GO terms of PC-iPS vs PEF-iPS cells. (B, d) KEGG pathway enrichment of signal pathways (****p < 0.0001, ***p < 0.001, **p < 0.5; ns, not significant)

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