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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Systemic administration of quality- and quantity-controlled PBMNCs reduces bisphosphonate-related osteonecrosis of jaw-like lesions in mice

Fig. 6

Effects of QQ-controlled PBMNC transplantation on CY/ZA affected-long bones. a Representative H-E-stained images (bar, 400 μm). BA/TA was the same, irrespective of QQ-controlled PBMNC transplantation. b Representative TRAP-stained images (BM: bone marrow; bar, 100 μm). QQ-controlled PBMNC transplantation did not significantly alter the number of osteoclasts. c The relative gene expression levels of CTSK, TRAP, F4/80, TNF-α, and IL-10 were the same between QQ-controlled PBMNC and VC. The Mann-Whitney U test was used for IL-10 analysis. Student’s t test was performed for all other analyzed parameters. n = 7/group; QQ: QQ-controlled PBMNC therapy

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