Roles for miRNAs in osteogenic differentiation of bone marrow mesenchymal stem cells

Table 2 Pro-osteogenic differentiation miRNAs

miRNAs	Target gene/target protein	Expression level	References
miR-27a	PPARγ, GREM1	↑	[56]
miR-21	P-Akt, HIF-1α	↑	[57]
miR-217	DKK1	↑	[61]
miR-26a	Runx2, OC, GSK3β	↑	[62, 63]
miR-148a	IGF1	↓	[64]
miR-200b	Cx43, VEGF-A	↓	[65]
miR-335-5p	DKK1	↑	[66]
miR-92a	Smad6 3′-UTR	↑	[68]
miR-9	Runx2, ERK	↑	[37]
miR-199b-5p	GSK3β	↑	[69]

ISSN: 1757-6512