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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Epidermal stem cells in wound healing and their clinical applications

Fig. 3

Schematic of crosstalk between the Wnt and Notch pathways and their function in regulating EPSCs during wound healing. Wnt and Notch signaling can affect the proliferation, differentiation, and migration of EPSCs, as well as HF regeneration by targeting c-Myc and Hes1, which ultimately lead to enhanced or delayed wound healing. The interaction between the Wnt and Notch pathways plays a vital role in wound healing, and jagged1 is the key mediator in this crosstalk

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