Fig. 5

Vascular markers at 6 weeks post-stroke by immunofluorescence. Representative images and quantification of immunofluorescence of CD31, collagen-IV, and α-SMA. At 6 weeks post-stroke, the hyperglycemic rats showed significantly increased arterial wall thickness compared with the non-hyperglycemic and treated hyperglycemic groups. 4′,6-diamidino-2-phenylindole (DAPI) was used for nuclear staining (3 animals per group, 4 sections in each animal per group). Data are shown as mean ± SD. *p < 0.05. Abbreviations: α-SMA: α-smooth muscle actin