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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Long noncoding RNA CCDC144NL-AS1 knockdown induces naïve-like state conversion of human pluripotent stem cells

Fig. 6

The epigenetic landscape of CCDC144NL-AS1-downregulated human ESCs. a Average H3K4me3 and H3K27me3 signals at all RefSeq and developmental genes in CCDC144NL-AS1-KD-H9 and NC-H9 cells. Log2RPKM ratio: log2(RPKMsample/RPKMinput). b Read count frequency of H3K4me3 and H3K27me3 signals across all RefSeq and developmental genes in CCDC144NL-AS1-KD-H9 and NC-H9 cells. ChIP-Seq tracks for H3K4me3 and H3K27me3 in CCDC144NL-AS1-KD-H9 and NC-H9 cells at genes associated with naïve pluripotency (c) and core pluripotency (d). e ChIP-Seq tracks for H3K4me3 and H3K27me3 in CCDC144NL-AS1-KD-H9 and NC-H9 cells at genes related to the development

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