Table 2 Selected top 10 of GO enrichment
From: High temperature suppressed SSC self-renewal through S phase cell cycle arrest but not apoptosis
GO-ID | GO term | Type | Up-genes | Down-genes | P value |
|---|---|---|---|---|---|
GO:0042026 | Protein refolding | Biological process | Dnajb1, Dnaja1, Hspa1l, Hsp90aa1 | – | 1.96E−06 |
GO:0061077 | Chaperone-mediated protein folding | Biological process | Clu, Hsph1, Dnajb1, Unc45b | – | 9.11E−05 |
GO:0042531 | Positive regulation of tyrosine phosphorylation of STAT protein | Biological process | Hes1, Osm, Il6ra, Il13 | – | 0.00011 |
GO:0051082 | Unfolded protein binding | Molecular function | Serpinh1, Dnajb1, Hsp90aa1, Dnaja1, Hspa1l | – | 4.71E−05 |
GO:2001244 | Positive regulation of intrinsic apoptotic signaling pathway | Biological process | Bbc3, Skil, Clu, Bcl2l11 | – | 0.00022 |
GO:0007260 | Tyrosine phosphorylation of STAT protein | Biological process | Il6ra, Il13, Osm, Hes1 | – | 0.00032 |
GO:0004896 | Cytokine receptor activity | Molecular function | Gfra2, Il18r1, Ccr4, Il1rl1, Ccr9, Il6ra | – | 2.44E−05 |
GO:0006986 | Response to unfolded protein | Biological process | Hsph1, Crebrf, Hsp90aa1, Hspa4l | Chac1 | 0.00014 |
GO:0009408 | Response to heat | Biological process | Hsp90aa1, Osm, Socs3, Trp53inp1, Dnaja1 | – | 0.00024 |
GO:0046425 | Regulation of JAK-STAT cascade | Biological process | Gfra2, Socs3, Il13, Il6ra, Osm, Hes1 | – | 0.00014 |