Table 1 Characteristics of mouse experiments
First author | Year | Location | Mice (sex, strain, weight) | Number of each group | Modeling method | Modeling duration | Type and source of MSCs | Way of MSCs administrated | Times of treatment | Parameter |
|---|---|---|---|---|---|---|---|---|---|---|
Guo-Chao Niu | 2012 | China | Male, C57B L/6, 18~22 g | DSS + Vechile (n = 10) DSS + MSCs (n = 10) | DSS (5%) | 30 | Mouse UC-MSCs | Tail vein injection | 1 | DAI, colon length, HS |
Xiao-Wen He | 2012 | China | Male, BALB/c mice, 19–21 g | DSS + 4%PBS (n = 6) DSS + MSCs (n = 6) | DSS (4%) | 7 | Mouse BM-MSCs | Tail vein injection | 3 | DAI, colon length, HS |
Xiao-Xi Xu | 2018 | China | Male, BALB/c mice, 18–22 g | DSS + 4%PBS (n = 8) DSS + ERCs (n = 8) | DSS (3%) | 7 | Mouse ERCs | Tail vein injection | 3 | DAI, colon length |
Jin Seok Park | 2015 | Korea | Male, C57BL/6 mice, N/A | DSS + PBS (n = 8) DSS + mc-MSCs (n = 8) | DSS (2.5%) | 6 | MC-MSCs | Tail vein injection | 3 | DAI, colon length, HS |
Young-Sun Nam | 2015 | South Korea | Female, C57BL/6, N/A | DSS + PBS (n = 10) DSS + MSCs (n = 10) | DSS (3.5%) | 6 | Mouse BM-MSCs | Intraperitoneal injection | 1 | DAI, colon length |
Wei-Xin Liu | 2015 | China | Male, C57BL/6 mice, N/A | DSS (n = 10) DSS + MSCs (n = 10) | DSS (N/A) | 7 | Mouse BM-MSCs | Tail vein injection | 1 | DAI |
Forte | 2015 | Italy | Male, C57BL/6 mice, N/A | DSS (n = 4) DSS + MSCs (n = 4) | DSS (1.5%) | 9 | Human AD-MSCs | Irrigation | 3 | DAI, HS |
Li Cao | 2019 | China | Male, BALB/c mice, 21–23 g | DSS + NS (n = 10) DSS + EVs (n = 10) | DSS (3%) | 7 | EVs from Mouse BM-MSCs | Intraperitoneal injection | 7 | DAI, colon length |