Table 3 Characteristics of clinical trials
First author | Year | Location | Type of study | Number of MSC group | Number of control group | Male/female | Age | Type and source of MSCs | Way of MSCs administrated | Outcomes | Adverse events | MINORS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Knyazev, O. | 2017 | Russia | Meeting abstract | 26 | N/A | N/A | 20–62 (mean 28) | BM-MSCs | Submucosal injection by colonoscopy | One-year healing rate 23/26 | N/A | 9 |
Yang, Bo. | 2015 | China | Full text | 7 | 10 | 13/4 | 37–62 | BM-MSCs | Submucosal injection by colonoscopy | 14-month healing rate 7/7, 3/10 | N/A | 16 |
Lazebnik, L. | 2011 | Russian | Meeting abstract | 44 | N/A | N/A | N/A | BM-MSC | N/A | One-year healing rate 32/44 | N/A | 9 |
Jun Liang | 2012 | China | Letter | 3 | N/A | 1/2 | 22–44 (mean 29) | BM-MSC | N/A | One-year healing rate 2/3 | N/A Insomnia; low; fever | 7 |
Lazebnik, L. | 2010 | Russian | Meeting abstract | 44 | N/A | N/A | N/A | BM-MSC | Intravenous Infusions | Two-year healing rate 34/44 | N/A | 9 |
Knyazev, Oleg | 2013 | Russian | Meeting abstract | 58 | 50 | N/A | 19–64 (mean 36) | BM-MSC | Intravenous Infusions | One-year healing rate 44/58, 17/50 | N/A | 16 |
Jian-Xia Hu | 2016 | China | Full text | 34 | 36 | 21/13 22/14 | 42.9 ± 23.1 and 43.7 ± 28.7 | UC-MSCs | Intravenous infusions | One-year healing rate 85.3%, 16.7% | N/A | 22 |