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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity

Fig. 6

In vivo modulation of inflammatory responses by 3D-ADSC1000: a Flow cytometric analysis of surface markers (CD11b+F4/80+) for the determination of total macrophages in the liver of mice. The percentage represents CD11b+F4/80+ population, and the graph represents mean ± SEM (n = 4) (one-way ANOVA). b Expression of CD86 from F4/80+ population. The graph represents the mean ± SEM (n = 4). c Expression of CD206 from F4/80+ population. The graph represents the mean ± SEM (n = 4). d Percentage of F4/80+ CD86+ population (mean ± SEM) (n = 4) (one-way ANOVA). e Percentage of F4/80+ CD206+ population (mean ± SEM) (n = 4) (one-way ANOVA). f Serum concentration of IL-10 after 7 h of MSC transplantation (n = 5). *p < 0.05, **p < 0.01, and ***p < 0.001. MFI median fluorescence intensity

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