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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: miR-140-5p regulates the odontoblastic differentiation of dental pulp stem cells via the Wnt1/β-catenin signaling pathway

Fig. 4

Wnt1 was the target gene of miR-140-5p. a Luciferase reporter gene detection results suggested that the luciferase activity of the mimic group was significantly lower than that of the mimic NC group. b Western blot analysis showed the expressions of Wnt1 and total β-catenin proteins were the highest in the inhibitor group and the lowest in the mimic group; the differences among the control, mimic NC, and inhibitor NC groups were not statistically significant. c Western blot analysis showed the expression of nuclear β-catenin protein was the highest in the inhibitor group and the lowest in the mimic group; the differences among the control, mimic NC, and inhibitor NC groups were not statistically significant. *vs. the control group, P < 0.05; #vs. the mimic NC group, P < 0.05; @vs. the inhibitor NC group, P < 0.05; &vs. the mimic group, P < 0.05. n = 6

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