Fig. 5From: Human placenta-derived mesenchymal stem cells ameliorate orbital adipogenesis in female mice models of Graves’ ophthalmopathyHuman PMSCs have effects on adipogenesis of orbital fibroblasts. The orbital fibroblasts from normal and GO patients were co-cultured with hPMSCs during 2 days of adipose differentiation. After 10 days, a cells were stained with Oil Red O solution or b cell lysates were subjected to mRNA expression analysis to determine ADIPONECTIN, PPARγ, C/EBPα, and TGFβ2 genes. Significantly different values between the groups are indicated with asterisks (*p < 0.05, **p < 0.005, ***p < 0.0005)Back to article page