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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Human amniotic epithelial cells improve fertility in an intrauterine adhesion mouse model

Fig. 6

hAECs ameliorated the pregnancy outcomes in the IUA mouse model. A (a, b) For normal day-9 pregnant uterine masses, the implanted fetuses were of similar size and shape, lined up in order. (c, d) In IUA uterine horns, the number of fetuses was fewer, and the two uterine horns of one mouse were asymmetric; the sizes of the fetuses varied. (e, f) In the hAEC group, the number of fetuses increased. B The fetus size was significantly smaller in the IUA group (0.67 ± 1.211) than in the control group (11.33 ± 3.204), and the litter size of the hAEC-treated group was significantly greater (5.1 ± 4.535) (n = 6; *p < 0.05; **p < 0.01; ***p < 0.001; NS, p ≥ 0.05). C The pregnancy rate of each group was calculated. The pregnancy rate was significantly lower in the IUA group than in the normal control. After treatment with hAECs, the pregnancy rate recovered to 66.67%

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