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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies

Fig. 1

The mechanism of miRNAs in stem cell-derived extracellular vesicles for acute kidney injury. Extracellular vesicles secreted by stem cells carry miRNAs and deliver them into renal cells. These miRNAs inhibit target mRNA translation or induce target mRNA degradation through complementarity to the region of target mRNAs. This process can play an anti-inflammatory, anti-apoptotic, and anti-fibrotic effects on AKI

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