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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT

Fig. 5

Intercellular transfer of miR-133 by H/R-induced EPC-derived exosomes inhibits fibroblast MEndoT. a Endothelial markers CD31, VE-cadherin, and vWF and fibrosis markers α-SMA, N-cadherin, vimentin, and collagen I were measured by western blotting in fibroblasts treated with normal cultured EPC-derived exosomes, H/R-induced EPC-derived exosomes, H/R+NC inhibitor-induced EPC-derived exosomes, and H/R+miR-133 inhibitor-induced EPC-derived exosomes. b–h The bar graph represents quantification of endothelial markers CD31 (b), VE-cadherin (c), and Vwf (d) and fibrosis markers α-SMA (e), N-cadherin (f), vimentin (g), and collagen I (h) expression per group. ***P < 0.001, &&&P < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512