Fig. 1
MSCs ameliorated CCl4-induced ALI. a Determination of the efficacy of MSCs in ALI. b Effect of MSC transplantation on the survival rate at 7 days (n = 22 per group). *P < 0.05 compared to the placebo (PBS) group by the Kaplan-Meier test. c Serum levels of ALT and AST at days 1, 2, 3, and 7 after transplantation; data are means ± SEM (n = 3–5 per group). *P < 0.05 compared to the placebo (PBS) group by the Mann-Whitney U test. d HE-stained images of the liver at days 1, 2, 3, and 7 after MSC (M) or PBS (P) administration. e Percentages of necrotic areas at days 2, 3, and 7 after transplantation. Data are means ± SEM (n = 3–5 per group). *P < 0.05 compared to the placebo (PBS) group by the Mann-Whitney U test