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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Immunomodulatory effect of mesenchymal stem cells in chemical-induced liver injury: a high-dimensional analysis

Fig. 4

High-dimensional characteristics of MSC-specific alterations in T cell subsets. a viSNE maps of normalized expression levels of CD103, CD5, CD127, CD38, CD4, CD8, ICOS, and Ly6C. b Absolute numbers of Ly6ClowCD8+ TRM, Ly6ChiCD8+ TRM, and naïve CD4+ T cells over time (n = 8–9, *P < 0.05, **P < 0.01, and ***P < 0.001 by the paired t test). c Bar plots of normalized expression of cell-surface markers in the indicated cell subsets (n = 8–9, *P < 0.05, **P < 0.01, and ***P < 0.001 by the paired t test). d Bar plots of normalized KI67 expression. e viSNE map; colors indicate the KI67 expression levels. f Correlation plot of Ly6ClowCD8+ TRM and Ly6ChiCD8+ TRM cells

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