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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1

Fig. 1

Autophagy regulates MSC-mediated CD4+ T cell recruitment. a CD4+ T cells were purified from PBMCs and the purity was assessed by flow cytometry. b After co-culturing with MSCs for 4 h, the number of migrated CD4+ T cells was analyzed by flow cytometry. 3-MA weakened MSC-mediated migration, while rapamycin enhanced migration compared with the control group without treatment. The MSC culture supernatants showed similar results. Statistical significance among groups was determined by using SPSS. Values are presented as the means ± SD of 18 samples per group. * indicates P < 0.05. (Only growth medium without MSCs was used in the blank group)

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Stem Cell Research & Therapy

ISSN: 1757-6512