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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1

Fig. 3

MSC autophagy increases the ratio of Treg cells. Nonactivated CD4+ T cells were used as the blank group. a, c The flow cytometry results revealed the ratio of Treg cells decreased in the 3-MA group but increased in the rapamycin group compared with the control group without treatment. b, d There were no differences in the Th17 ratio among groups. e The change in the Treg/Th17 ratio was similar to the change in Treg ratio among the control and MSC groups. Values are presented as the means ± SD of 18 samples per group. * indicates P < 0.05

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