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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1

Fig. 4

MSC autophagy decreases the ratio Th1 cells. Flow cytometry was used to detect Th1 and Th2 cells in the co-culture systems. a, c MSCs remarkably inhibited Th1 cell differentiation. The 3-MA group showed a higher ratio of Th1 cells while the rapamycin group showed a lower ratio of Th1 cells than the control group. b, d The differences in Th2 cells among MSC groups were not statistically significant. e The change in the Th1/Th2 ratio was similar to the change in the Th1 ratio among the control and MSC groups. Values are presented as the means ± SD of 18 samples per group. * indicates P < 0.05

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