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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1

Fig. 5

Autophagy decreases the inflammatory cytokines in co-culture. On the 5th day of co-culture, a CBA kit was used to measure the levels of cytokines in the co-culture system. IL-17A, IFN-γ, and IL-2 increased in the 3-MA-pretreated group but decreased in the rapamycin-pretreated group compared with the control group. The results suggested that autophagy of MSCs could regulate the secretion of the inflammatory cytokines in co-culture. Values are presented as the means ± SD of 18 samples per group. * indicates P < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512