Fig. 5

ICAM-1-overexpressing MSCs have significantly increased migration toward the spleen in IBD mice. The infused primary MSCs, C3 cells, C3-vector cells, and C3-ICAM-1 cells are detected in the spleen of IBD mice; however, the results in frozen sections indicate that ICAM-1-overexpressing MSCs showed stronger migration toward the spleen in IBD mice. a, b ICAM-1-overexpressing MSCs are indicated by arrows in a. Bars in a represent 200 μm. (*, P < 0.05, **, P < 0.01)