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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: miR-205-5p inhibits human endometriosis progression by targeting ANGPT2 in endometrial stromal cells

Fig. 1

Identification of miR-205-5p as a negatively pathologic miRNA in endometriosis. a The different miRNA expression profiles between the EN (n = 3) and EC (n = 3) groups were analysed by miRNA microarray. The heatmap diagram shows that the representative miRNAs were significantly associated with endometriosis. EN1, EN2, and EN3 indicate 3 normal endometria; EC1, EC2, and EC3 indicate 3 ectopic endometria. b The levels of 16 differentially expressed miRNAs in the endometrium used for microarray analysis were analysed by qRT-PCR. c, d The levels of miR-205-5p, miR-4497, miR-3154, and miR-3926 were validated by qRT-PCR in additional tissues and serum from the EN (n = 23) and EC (n = 68) groups. EN, normal endometrium; EC, ectopic endometrium. Error bars represent the mean ± SD of 3 independent experiments. n.s., not significant; *P < 0.05; **P < 0.01; ***P < 0.001

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