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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: miR-205-5p inhibits human endometriosis progression by targeting ANGPT2 in endometrial stromal cells

Fig. 5

The re-expression of ANGPT2 could rescue the suppressive effects of miR-205-5p in endometriosis. a The levels of miR-205-5p in cells with indicated treatment were analysed by qRT-PCR. b The expression of ANGPT2 and AKT/ERK pathway-associated protein in Lenti-miR-205-5p-treated cells transfected with plasmid-ANGPT2 or vector control and SiANGPT2- or SiRNA-treated cells were detected by western blot analysis. ce Re-expression of ANGPT2 rescued, whereas knockdown of ANGPT2 simulated the functional effects induced by miR-205-5p overexpression through wound healing, Transwell invasion and apoptosis assay. miR-205, miR-205-5p. These experiments were conducted after the indicated treatment for 48 h. Error bars represent the mean ± SD of three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001

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