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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Autograft microskin combined with adipose-derived stem cell enhances wound healing in a full-thickness skin defect mouse model

Fig. 1

Treatment of ADSC+MS promoted wound healing in a full-thickness skin defect mouse model. a Mice were randomized into two parts (n = 15 each part). One group accepted the treatment of microskin or PBS, the other accepted microskin plus ADSCs or ADSCs after surgery. Photograph of the wound area was performed at days 0, 7, and 14, and mice were sacrificed to have IHC procedure at days 7 and 14. b Representative of a full-thickness wound of each group at day 0, and wound closure can be observed at days 7 and 14 which the MS+ADSC group presented the most remarkable effect of wound healing. c Quantitative evaluation of the wound area on days 0, 7, and 14 post-treatment. ###p < .001, the MS+ADSC group compared to all other groups; ****p < .0001, the MS+ADSC group compared to the ADSC group and control group; ***p < .001, the MS+ADSC group compared to the MS group. d Quantitative evaluation of wound contraction at day 14 post-treatment. ****p < .0001; **p < .01; *p < .05, compared to the control group

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