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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice

Fig. 5

ac ASC infusion reduces bacterial loads which is not affected by preincubation with an anti-tissue factor antibody. Bacterial loads (colony-forming units (CFUs)) in the lung, blood, and liver 48 h after infection with K. pneumoniae via the airways in mice treated with 1 × 106 cryopreserved ASCs intravenously 6 h after bacterial inoculation. ASCs were preincubated with a blocking anti-tissue factor antibody or isotype control antibody prior to infusion. Data are expressed as box-and-whisker diagrams, N = 8 mice per group. *p < 0.05 versus the control group

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