Fig. 2
From: Enhancement of therapeutic potential of mesenchymal stem cell-derived extracellular vesicles
Components of MSC-derived EVs and their related therapeutic potential. The different circles show the suggested vesicular protein, mRNA, and miRNA components mediating the immune modulation, regeneration, and tumor growth effects of MSC-EVs. Abbreviations: MSC, mesenchymal stem cell; EVs, extracellular vesicles; PDGF-D, platelet-derived growth factor-D; COX2, cyclooxygenase 2; PGE2, prostaglandin E2; CCR2, C-C chemokine receptor type 2; KGF, keratinocyte growth factor; Ang-1, angiopoietin-1; HGF, hepatocyte growth factor; IGF-1R, insulin-like growth factor 1 receptor; IL-10, interleukin-10; UBR2, ubiquitin protein ligase E3 component n-recognin 2; FGF19, fibroblast growth factor 19