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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: A novel construct with biomechanical flexibility for articular cartilage regeneration

Fig. 1

Structure of the platelet-rich fibrin (PRF). a A cell sheet that could be fully stripped was formed after 14 days of induction with cell sheet induction medium. b Inverted microscope observation showed the intertwined arrangement and stable growth morphology of the cell sheet (× 40, bar = 200 μm). c Blood samples (10 ml) were extracted from the central auricular arteries of rabbits and immediately centrifuged at 3000 r/min for 10 min. d PRF clot between the top layer of serum containing a few cells and the bottom layer of red corpuscles. e Complete removal of the PRF clot. f Preparation of the BMSC/PRF construct. g–i Cross-sectional observation by SEM. g Horizontal view at low magnification (× 1000). h Longitudinal view at low magnification (× 2000). i Longitudinal view at high magnification (× 20,000) (red arrow: BMSCs; yellow arrow: PRF)

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