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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model

Fig. 5

Inflammation in kidneys of rhesus macaques. RT-qPCR (a) and immunohistochemistry (b) analyses of the expression levels of inflammatory factors in renal biopsies before and after NS or MSC transplantation. NS: normal saline; MSCs: mesenchymal stem cells; Before Tx: 1 week before MSC transplantation; After Tx: 1 month after MSC transplantation. Scale bar = 50 μm. Each bar represents the mean ± s.e.m. Four fields of each section, four sections per rhesus macaque were observed and quantified, and the number of rhesus macaques was analyzed in each group: Normal (n = 3), DN + NS (n = 4), DN + MSCs (n = 6). *p < 0.05: before versus after in the DN + MSC group. #p < 0.05: DN + NS group versus DN + MSC group, before or after in the DN + MSC group versus normal group

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