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Table 4 Longitudinal change between base time and 48 weeks in compositional MRI measurements and clinical outcomes

From: Multi-compositional MRI evaluation of repair cartilage in knee osteoarthritis with treatment of allogeneic human adipose-derived mesenchymal progenitor cells

Measurement

Base time

48 weeks

P value

T1rho (ms)

39.73 ± 2.97

37.99 ± 2.61

< 0.0001*

T2 (ms)

42.01 ± 4.50

38.86 ± 2.82

0.0001*

T2star (ms)

24.25 ± 2.25

22.49 ± 1.52

< 0.0001*

R2star (s−1)

46.08 ± 5.70

48.87 ± 6.35

0.0001*

ADC (×10−3 mm2/s)

1.56 ± 0.12

1.44 ± 0.12

0.0003*

FA

0.46 ± 0.04

0.50 ± 0.04

0.002*

WORMS

12.58 ± 3.57

12.84 ± 3.61

0.146

CV (mm3)

31,441 ± 5578

31,517 ± 5828

0.781

WOMAC

42.94 ± 16.42

25 ± 14.26

< 0.0001*

SF-36

89.83 ± 12.19

72 ± 12.69

< 0.0001*

  1. Values are given as mean ± standard deviation of the mean
  2. *Significantly different between two groups (P < 0.05)