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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Metabolomic profiles of induced pluripotent stem cells derived from patients with rheumatoid arthritis and osteoarthritis

Fig. 5

A mitochondrial function assay of OA and RA iPSCs. a Oxygen consumption rate (OCR) of OA and RA iPSCs was measured by a Seahorse XF analyzer. Oligomycin, FCCP, and Rotenone + Antimycin A were treated at the indicated point. b Statistical analysis of basal respiratory in the OCR curve. c Statistical analysis of spare respiratory capacity level in the OCR curve. d Statistical analysis of ATP production levels in the OCR curve. e Statistical analysis of proton leak level in OCR curve. OCR curve was presented as mean of OA iPSCs (n = 3) and RA iPSCs (n = 3). Data presented mean ± SEM. All data was analyzed by ANOVA test. *p < 0.05, **p < 0.01, ***p < 0.001

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Stem Cell Research & Therapy

ISSN: 1757-6512