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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Dimethyloxaloylglycine-stimulated human bone marrow mesenchymal stem cell-derived exosomes enhance bone regeneration through angiogenesis by targeting the AKT/mTOR pathway

Fig. 1

Internalization and proangiogenic effects of MSC-Exos in HUVECS. a Fluorescent microscopy showing internalization of DIO-labeled DMOG-MSC-Exos by HUVECS. Green-labeled exosomes are visible in the perinuclear region of HUVECs. b Proliferation of HUVECS treated with exosomes (50 μg/mL). c Wound healing assay of HUVECs treated with exosomes (50 μg/mL). d Quantitative analysis of wound closure. e Tube formation capacity of HUVECs treated with exosomes. f Quantitative analysis of total tube length (*P < 0.05, versus control; #P < 0.05, versus MSC-Exos)

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Stem Cell Research & Therapy

ISSN: 1757-6512