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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Stromal vascular fraction promotes migration of fibroblasts and angiogenesis through regulation of extracellular matrix in the skin wound healing process

Fig. 8

hADSCs promote migration of fibroblasts. a Diagram of the transwell setup. hF cells were seeded into the lower chamber of the 24-well transwell (pore size: 0.8 μm); hFs or hADSCs were plated in the upper chamber. b Representative images showing fibroblast scratches. Images were taken at 0 to 72 h. Arrow shows the width of the scratch wound. c Quantification of the scratch width over time measured using Image-Pro Plus 6 software. (*P < 0.05, compared to B-hFs; #P < 0.05, compared to hFs-hFs). d Significantly enriched KEGG pathways are shown as a bubble diagram. The X-axis represents the enrichment score of the gene sets, the Y-axis shows gene set names, and the size of the bubble indicates the number of genes in that gene set. The KEGG pathways with P < 0.05 are significantly enriched. e Venn diagram displaying the number and overlap of the enriched KEGG pathway in the Fs-CON vs Fs-hADSC group (blue), M-CON vs M-hADSC group (green), and M-CON vs M-SVF group (yellow)

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