Fig. 6

No differences among different routes of BMSC supernatant administration. On the third day after immunization, BMSC supernatant was treated by nasal mucosa, tail vein injection, and intraperitoneal injection. The nasal mucosa was unilaterally 30 μl per day, bilaterally administered; the intraperitoneal and tail vein doses were 60 μl per day, and the clinical score and body weight were terminated after the administration to the control group. Mean ± SEM, n = 8, ***P < 0.001