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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Age-related transcriptome changes in Sox2+ supporting cells in the mouse cochlea

Fig. 5

Cell cycle genes, Wnt pathway genes, and TGFβ pathway genes in P3, P7, P14, and P30 Sox2+ SCs. a The expression of 72 genes involved in the cell cycle in P3, P7, P14, and P30 Sox2+ SCs. b The differentially expressed genes in P3, P7, P14, and P30 Sox2+ SCs that are involved in Wnt signaling pathways. c The differentially expressed genes in P3, P7, P14, and P30 Sox2+ SCs that are involved in TGFβ signaling pathways. d Quantitative RT-PCR analysis of some cell cycle and Wnt pathway genes that are differentially highly expressed in P3, P7, P14, and P30 Sox2+ SCs as identified by RNA-seq analysis. Student’s paired t test; * = P7, P14, and P30 Sox2+ SCs vs. P3 Sox2+ SCs; & = P14 and P30 Sox2+ SCs vs. P7 Sox2+ SCs; ^ = P30 Sox2+ SCs vs. P14 Sox2+ SCs. *p < 0.05, **p < 0.01, ***p < 0.001, &p < 0.05, &&&p < 0.001, ^p < 0.05, ^^^p < 0.001

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