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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: The factors present in regenerating muscles impact bone marrow-derived mesenchymal stromal/stem cell fusion with myoblasts

Fig. 3

The IGF-1, IL-4, IL-6, or SDF-1 impact on adhesion and structural protein expression in human BM-MSCs (hBM-MSCs). a The expression of ADAM9, CD9, NCAM, VCAM, CDH15 (m-cahderin), desmin, and MYH3 (muscle embryonic myosin heavy chain 3) in hBM-MSCs non-treated (NT) or treated with either IGF-1, IL-4, IL-6, or SDF-1, cultured for 7 days in the proliferating medium (PM) (n = 3). b The expression of mRNAs encoding ADAM9, CD9, NCAM, VCAM, m-cadherin (CDH15), desmin, and MYH3 in hBM-MSCs non-treated (NT) or treated with either IGF-1, IL-4, IL-6, or SDF-1, cultured for 7 days in the differentiating medium (DM) (n = 3). c The expression of ADAM9, CD9, and CDH15 in hBM-MSCs non-treated (NT) or pre-treated with either IGF-1, IL-4, IL-6, or SDF-1 for 3 days, then cultured in the proliferating medium (PM) and analyzed after 1, 3, and 7 days (n = 3); *p < 0.05, **p < 0.01, ***p < 0.005

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