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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Mesenchymal stem cell-derived exosomal microRNA-133b suppresses glioma progression via Wnt/β-catenin signaling pathway by targeting EZH2

Fig. 8

The schematic representation of mechanism by which MSC-derived exosomes containing miR-133b affect glioma cell activities. MSCs transfer miR-133b to glioma cells through exosomes to inhibit the EZH2 expression via suppression of the Wnt/β-catenin signaling pathway, whereby the glioma cell proliferation, migration, and invasion are diminished, and ultimately, the progression of glioma is attenuated

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