Fig. 7

Motor-evoked potential (MEP) recordings. a Representative motor-evoked potential (MEP) waves obtained 2 days before spinal cord injury (SCI; n = 16), 2 days after SCI (n = 16), and at 6 weeks post-transduction (WPT) in the Mock (n = 5) and Zfp (n = 11) groups. In intact traces (2 days before SCI), two separated waves, N1 and N2, were elicited by each stimulation. Note that N1 MEPs are a single transcranial electrical pulse, while N2 MEPs are polyphasic pulses. Neither wave could be elicited 2 days after the SCI. At 6 WPT, only N1 MEPs were detected in the Mock and ZFP groups. b In the Zfp-treated group, the amplitude of N1 MEPs increased significantly at 6 WPT. c In the Zfp-treated group, the latency of N1 MEPs decreased significantly at 6 WPT. Data are shown as mean ± SD. Data were analyzed by ANOVA and the Mann-Whitney U test as post hoc. *p < 0.05, **p < 0.01, and ***p < 0.001